Recherche Associate In Cellular Assay Development — Roche
- Lieu
- Basel
- Contrat
- full-time
- Publié
- Hier
Vue d’ensemble du poste
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
- Your key responsibilities include:
- Developing, optimizing, and validating robust cell-based functional assays—including complex 3D models—using technologies such as HTRF, AlphaLISA, Luminescence, and High-Content Imaging.
- and skills:
- Master’s degree in Cell Biology, Molecular Biology, or a closely related scientific discipline.
Responsabilités principales
- Your key responsibilities include:
- Developing, optimizing, and validating robust cell-based functional assays—including complex 3D models—using technologies such as HTRF, AlphaLISA, Luminescence, and High-Content Imaging.
- Miniaturizing cellular assays into high-density plate formats (384-well and 1536-well plates), optimizing performance parameters such as Z’-factor and signal-to-background ratio.
- Maintaining, characterizing, and performing quality control on a wide range of mammalian cell lines, including primary cells, continuous lines, and induced pluripotent stem cells (iPSCs).
- Partnering closely with the High-Throughput Screening and Profiling team to seamlessly transfer new assays onto integrated robotic systems.
- Running routine cellular assays to generate high-quality data supporting structure-activity relationship (SAR) studies for portfolio projects.
- Analyzing complex screening datasets using modern scientific tools (e.g., Genedata Screener,
- Spotfire) and documenting workflows meticulously in Electronic Lab Notebooks (ELN).
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups. Who You Are
- You are a curious, highly motivated scientist who thrives on solving complex biological challenges.
Exigences principales
- and skills:
- Master’s degree in Cell Biology, Molecular Biology, or a closely related scientific discipline.
- 5+ years of relevant industry research experience focused on advanced cell culture and cell-based assay development.
- Demonstrated experience in miniaturizing assay workflows into 384- and 1536-well plate formats and utilizing automated liquid-handling systems.
- Strong proficiency in data analysis, statistical evaluation, and presenting scientific findings clearly to multidisciplinary teams.
- Fluency in English with strong interpersonal and communication skills.
- Flexibility and a resourceful problem-solving approach tailored to a dynamic lab environment.
- Nice to have: Hands-on experience with iPSC differentiation, 3D
Processus de candidature
- You bring a collaborative mindset, value diverse perspectives, and are eager to apply your expertise to discover life-changing treatments.
Entreprise et contexte
- In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.
- At pRED, we are united by our mission to transform science into medicines.
- Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
- Therapeutic Modalities (TMo) organization, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact. The Opportunity
- Joining Small Molecule Research Discovery within Therapeutic Modalities, you will work within a highly engaged, cross-functional team bridging cell biology, automation, and multiple therapeutic areas.
- In this role, you drive innovation through strong commitment to lab science by developing the foundational cellular models that power our drug discovery pipeline.
Détails supplémentaires
- Join Roche, where every voice matters.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups. Qualifications and skills:
Notes et contenu original
- The Position
- The Opportunity
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups.
- Who You Are
- Qualifications and skills:
Questions sur cette offre
Quel salaire propose Roche pour ce poste ?
Roche indique CHF 64 500 - 110 000 bruts par an pour ce poste à Basel. Il s'agit du salaire publié dans l'annonce d'origine (ou, si l'employeur ne précise pas de montant, d'une estimation réaliste pour le rôle et le secteur) — le calculateur de ce site le convertit en net réel une fois l'impôt frontalier et les cotisations sociales appliqués.
Est-ce un poste à temps plein, et quel type de contrat propose Roche ?
Cette offre est un poste en temps plein. Le type de contrat affiché ici provient directement de l'annonce originale de l'employeur ; confirmez toujours les horaires exacts, le préavis et la durée d'essai avec Roche pendant le processus de candidature, ces détails pouvant varier même au sein de la même catégorie de contrat.
Ai-je besoin d'un permis de frontalier pour un poste dans le canton de Bâle ?
Les résidents UE/AELE domiciliés dans la zone frontalière du pays voisin du canton de Bâle peuvent demander un permis G ; l'employeur suisse le dépose auprès de l'office cantonal des migrations après signature du contrat. Les règles de zone frontalière et les délais varient selon le pays voisin et le canton — confirmez les détails auprès de l'office des migrations du canton de Bâle ou avec les RH pendant la candidature.
Comment postuler à ce poste chez Roche ?
Utilisez le bouton « Postuler maintenant » sur cette page — il renvoie directement à l'annonce originale de Roche sur roche.wd3.myworkdayjobs.com, votre candidature arrive donc directement dans le système de suivi des candidatures de l'employeur. Frontaliere Ticino ne collecte ni ne transmet lui-même les candidatures.
