Principal Scientist - Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics — Novartis
- Lieu
- Basel
- Contrat
- full-time
- Publié
- Hier
Vue d’ensemble du poste
Salary Range
CHF93,800.00
CHF174,200.00 Job Description Summary LI-Onsite Location: Basel, Switzerland Role Purpose:
- Salary Range:
- CHF93,800.00
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
Responsabilités principales
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- Mentor and lead a team of scientists specialized in oligonucleotide synthesis, purification, analysis, and conjugation at millimole scale.
- Collaborate with global discovery, development, and project teams to advance novel oligonucleotide chemistries and facilitate their successful transition from research into development.
- Identify and implement innovative technologies, workflows, and manufacturing approaches to enhance operational excellence, production capabilities, and turnaround times of siRNA, ASO and other oligonucleotide modalities supporting in vivo and preclinical studies.
Exigences principales
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
- Minimum 2–3 years of industry experience and proven expertise in mid- large-scale oligonucleotide solid phase synthesis, purification, analysis, conjugation, and other related processes.
- Extensive experience operating and maintenance of AKTA Oligopilot/Oligosynt systems and AKTA Avant purification platforms, with strong proficiency in Unicorn software.
- Strong hands-on experience with process development, method optimization and scale-up strategies of oligonucleotides.
- Demonstrated leadership experience, including mentoring, and team management.
- Strong communication skills and ability to work effectively in a matrixed cross-functional global teams’ environment.
Ce que l’entreprise offre
- & Rewards
- At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
- Expected Annual Base Salary Range for role: 93,800.00
- 174,200.00 CHF Annual
- The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
- In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
- The rewards of being part of our team go far beyond base pay and incentives.
- We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs.
- In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. Read our broch
Processus de candidature
- Communicate scientific findings and project updates effectively to internal and external stakeholders through presentations, technical reports, and patent applications.
- Maintain high-quality scientific documentation, including electronic laboratory notebooks (ELNs), experimental protocols, technical reports, and project summaries.
- Foster a culture of scientific excellence, collaboration, continuous learning, and solution-oriented problem solving.
Détails supplémentaires
- Job Description Summary Location: Basel, Switzerland
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs. Qualifications and Requirements:
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.
Notes et contenu original
- CHF174,200.00
- Job Description Summary
- Location: Basel, Switzerland
- Role Purpose:
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs.
- Job Description
- Qualifications and Requirements:
- Benefits & Rewards
- Read our broch
Questions sur cette offre
Quel salaire propose Novartis pour ce poste ?
Novartis indique CHF 85 500 - 129 500 bruts par an pour ce poste à Basel. Il s'agit du salaire publié dans l'annonce d'origine (ou, si l'employeur ne précise pas de montant, d'une estimation réaliste pour le rôle et le secteur) — le calculateur de ce site le convertit en net réel une fois l'impôt frontalier et les cotisations sociales appliqués.
Est-ce un poste à temps plein, et quel type de contrat propose Novartis ?
Cette offre est un poste en temps plein. Le type de contrat affiché ici provient directement de l'annonce originale de l'employeur ; confirmez toujours les horaires exacts, le préavis et la durée d'essai avec Novartis pendant le processus de candidature, ces détails pouvant varier même au sein de la même catégorie de contrat.
Ai-je besoin d'un permis de frontalier pour un poste dans le canton de Bâle ?
Les résidents UE/AELE domiciliés dans la zone frontalière du pays voisin du canton de Bâle peuvent demander un permis G ; l'employeur suisse le dépose auprès de l'office cantonal des migrations après signature du contrat. Les règles de zone frontalière et les délais varient selon le pays voisin et le canton — confirmez les détails auprès de l'office des migrations du canton de Bâle ou avec les RH pendant la candidature.
Comment postuler à ce poste chez Novartis ?
Utilisez le bouton « Postuler maintenant » sur cette page — il renvoie directement à l'annonce originale de Novartis sur novartis.wd3.myworkdayjobs.com, votre candidature arrive donc directement dans le système de suivi des candidatures de l'employeur. Frontaliere Ticino ne collecte ni ne transmet lui-même les candidatures.
