Postdoctoral position in multiplexed single-cell RNAseq-based antibody discovery — EPFL
- Location
- Lausanne
- Contract
- Full-time
- Posted
- 53 days ago
Full description
Mission
The lab of biomedical microfluidics (LBMM; www.epfl.ch/labs/lbmm ) at the Swiss Federal Institute of Technology in Lausanne (EPFL), is looking for postdocs with a primary training in single-cell biology, next generation sequencing or antibody discovery. Experience in droplet-microfluidics, including use of commercial devices such as the 10X Genomics platform is beneficial, but not absolutely crucial. LBMM has already developed powerful technology platforms in the field of biomedicine and genomics over the past years, also leading to the establishment of two startup companies ( www.veraxa.com and www.thera-me.ch ).
Having a comprehensive microfluidic toolbox at hand (and expanding it continuously), we are now inviting applications for highly multiplexed single-cell RNAseq-based antibody discovery. The idea behind this project is to exploit transcriptomic data sets for the discovery of new therapeutic antibodies.
The lab has a very translational focus, running a tech development lab on the EPFL campus and a translational lab in the AGORA cancer research center (with direct access to patient material). Furthermore, a strong network of clinical partners in Europe and the US has been established.
The successful candidate will closely interact with experts in microfluidics and bioinformatics, while spearheading the above project.
Main duties and responsibilities include
- Optimization of single-cell sequencing workflows
- FACS sorting of cells
- Preparation of NGS libraries
- Data analysis
- Experimental design of the screens together with bioinformaticians
Your profile
- Hands on experience in single-cell analysis and/or antibody discovery
- Good knowledge of single-cell RNAseq workflows such as 10X genomics or DropSeq, experienced in flow cytometry
- Good knowledge in cell biology and biochemistry
- Prior experience in microfluidics is advantageous but not absolutely required
- Good communication skills
- Highly motivated and keen to work in an interdisciplinary environment
We offer
- A multidisciplinary environment
- Exposure to the latest cutting-edge experimental procedures (e.g. custom single-cell microfluidic platforms)
- Preparation for a future career in academia, industry or our own startup company
Informations
Only applications submitted through the online platform are considered. You are asked to supply:
- A brief cover letter (pdf, up to 2 pages).
And in one PDF
- A CV with a publication list.
- A research statement (pdf, up to 3 pages).
- Contact details for 3 referees.
For any further information, please contact: Prof. Christoph Merten, [email protected]
Contract Start Date : 10/01/2026
Activity Rate : 100.00
Contract Type: CDD
Duration: 1 year, renewable
Reference: 2443
Questions about this listing
What salary does EPFL offer for this role?
The original listing does not state a salary. Our estimate for this role and sector in Lausanne is CHF 60'500 - 91'500 gross per year — an estimate, not a figure communicated by EPFL. The calculator on this site converts a gross salary into your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does EPFL offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with EPFL during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Vaud?
EU/EFTA citizens living in an EU/EFTA state can apply for a G permit and can work anywhere in Switzerland: border zones no longer apply to them, and they must return home at least once a week. The Swiss employer files the request with Canton Vaud's migration office after the contract is signed. Processing times vary by canton, so confirm the specifics with Vaud's cantonal migration office or with HR during the application.
How do I apply for this position at EPFL?
Use the "Apply now" button on this page — it links directly to EPFL's original listing at careers.epfl.ch, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
