Postdoctoral Researcher – Next-Generation CAR Immune Cell Therapies Against Malignant Brain Tumors (ERC-funded), — Universität Zürich
- Location
- Zurich
- Contract
- full-time
- Posted
- 50 days ago
Role overview
Department for Neurology
Start of employment September 1, 2026, or by arrangement
The Laboratory for Molecular Neuro-Oncology at the University of Zurich is seeking a highly motivated postdoctoral researcher to join an ERC-funded project developing next-generation chimeric antigen receptor (CAR) immune cell therapies against malignant brain tumors. What we Offer:
- Department for Neurology
- Start of employment September 1, 2026, or by arrangement
- Your responsibilities Specific project goals:
- Generate CAR immune cell communities, comprising mixtures of engineered T cells, NK cells, monocytes, and additional cell types, using sophisticated in vitro and in vivo engineering platforms.
- Intellectual curiosity, creativity and a proactive approach to problem-solving
- Motivation to contribute to a project with direct patient impact
Main responsibilities
- Your responsibilities Specific project goals:
- Generate CAR immune cell communities, comprising mixtures of engineered T cells, NK cells, monocytes, and additional cell types, using sophisticated in vitro and in vivo engineering platforms.
- Identify co-factors that boost CAR immune cell function using cutting-edge screening platforms.
- Investigate anti-tumor activity and immune-cancer-cell environmental crosstalk in vitro and in vivo using sophisticated disease models (organoids, slice cultures, patient-derived samples, mouse models) and modern technologies including flow cytometry, multiplexed imaging, spatial transcriptomics/proteomics and single-cell profiling.
- Analyze patient samples from an accompanying clinical trial evaluating CAR immune cell communities.
Key requirements
- Intellectual curiosity, creativity and a proactive approach to problem-solving
- Motivation to contribute to a project with direct patient impact
- PhD in immunology, computational immunology, cell/molecular/cancer biology, bioengineering, biomedical sciences, or a related field
- Experience with immune cell engineering, cellular immunotherapy, and/or advanced in vitro/in vivo disease models is highly desirable
- Familiarity with single-cell and/or spatial technologies is a plus
- Strong publication record demonstrating scientific productivity
- Excellent communication skills and the ability to thrive in an interdisciplinary team What we offer
- Find out more: https://www.uzh.ch/de/explore/work.html. Work-Life Balance
- Flexible working models (such as part-time positions, mobile working, job-sharing)
- Childcare at the kihz foundation of UZH and ETH More Learning and Development
- Wide range of continuing education courses of UZH and the Canton of Zurich
- Language Center run jointly with ETH Zurich Food
What the company offers
- Our employees benefit from a wide range of attractive offers.
Additional details
- The Laboratory for Molecular Neuro-Oncology at the University of Zurich is seeking a highly motivated postdoctoral researcher to join an ERC-funded project developing next-generation chimeric antigen receptor (CAR) immune cell therapies against malignant brain tumors.
- Mentorship from leaders in the field and full support for a successful career in academia or in the entrepreneurial space
- Our team also has a strong track record of translating preclinical innovation into patient care. Project Description: Your responsibilities Specific project goals:
- Excellent communication skills and the ability to thrive in an interdisciplinary team
- Find out more: https://www.uzh.ch/de/explore/work.html.
- Childcare at the kihz foundation of UZH and ETH Learning and Development
- Language Center run jointly with ETH Zurich
- Food and drinks at reduced prices in the UZH cafeterias Lunch-Check-card with UZH contribution
- Special conditions on the Academic Sports Association ASVZ Free seasonal flu vaccinations
- Rest and relaxation at the quiet room in the university tower
Notes and original content
- What we Offer:
- Background:
- Our team also has a strong track record of translating preclinical innovation into patient care.
- Project Description:
- Your responsibilities
- Specific project goals:
- Your profile
- Work-Life Balance
- Childcare at the kihz foundation of UZH and ETH
- Learning and Development
Questions about this listing
What salary does Universität Zürich offer for this role?
Universität Zürich lists CHF 91'500 - 128'000 gross per year for this position in Zurich. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Universität Zürich offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Universität Zürich during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Zürich?
EU/EFTA residents living in the border zone of the country adjoining Canton Zürich can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Zürich's cantonal migration office or with HR during the application.
How do I apply for this position at Universität Zürich?
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