Principal Scientist - Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics — Novartis
- Ort
- Basel
- Vertrag
- full-time
- Veröffentlicht
- Gestern
Rollenüberblick
Salary Range
CHF93,800.00
CHF174,200.00 Job Description Summary LI-Onsite Location: Basel, Switzerland Role Purpose:
- Salary Range:
- CHF93,800.00
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
Hauptaufgaben
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- Mentor and lead a team of scientists specialized in oligonucleotide synthesis, purification, analysis, and conjugation at millimole scale.
- Collaborate with global discovery, development, and project teams to advance novel oligonucleotide chemistries and facilitate their successful transition from research into development.
- Identify and implement innovative technologies, workflows, and manufacturing approaches to enhance operational excellence, production capabilities, and turnaround times of siRNA, ASO and other oligonucleotide modalities supporting in vivo and preclinical studies.
Wichtige Anforderungen
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
- Minimum 2–3 years of industry experience and proven expertise in mid- large-scale oligonucleotide solid phase synthesis, purification, analysis, conjugation, and other related processes.
- Extensive experience operating and maintenance of AKTA Oligopilot/Oligosynt systems and AKTA Avant purification platforms, with strong proficiency in Unicorn software.
- Strong hands-on experience with process development, method optimization and scale-up strategies of oligonucleotides.
- Demonstrated leadership experience, including mentoring, and team management.
- Strong communication skills and ability to work effectively in a matrixed cross-functional global teams’ environment.
Was das Unternehmen bietet
- & Rewards
- At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
- Expected Annual Base Salary Range for role: 93,800.00
- 174,200.00 CHF Annual
- The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
- In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
- The rewards of being part of our team go far beyond base pay and incentives.
- We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs.
- In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. Read our broch
Bewerbungsprozess
- Communicate scientific findings and project updates effectively to internal and external stakeholders through presentations, technical reports, and patent applications.
- Maintain high-quality scientific documentation, including electronic laboratory notebooks (ELNs), experimental protocols, technical reports, and project summaries.
- Foster a culture of scientific excellence, collaboration, continuous learning, and solution-oriented problem solving.
Weitere Details
- Job Description Summary Location: Basel, Switzerland
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs. Qualifications and Requirements:
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.
Notizen und Originalinhalt
- CHF174,200.00
- Job Description Summary
- Location: Basel, Switzerland
- Role Purpose:
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs.
- Job Description
- Qualifications and Requirements:
- Benefits & Rewards
- Read our broch
Fragen zu dieser Stellenanzeige
Welches Gehalt bietet Novartis für diese Stelle?
Novartis gibt CHF 85'500 - 129'500 brutto pro Jahr für diese Position in Basel an. Dies ist das im Original-Inserat veröffentlichte Gehalt (oder, falls der Arbeitgeber keinen Betrag nennt, eine realistische Schätzung für Rolle und Branche) — der Rechner auf dieser Seite berechnet daraus Ihr tatsächliches Netto nach Grenzgänger-Steuer und Sozialabgaben.
Ist das eine Vollzeitstelle, und welchen Vertragstyp bietet Novartis?
Diese Stelle ist eine Vollzeit-Position. Der hier angezeigte Vertragstyp stammt direkt aus dem Original-Inserat des Arbeitgebers; klären Sie genaue Arbeitszeiten, Kündigungsfrist und Probezeit während des Bewerbungsprozesses mit Novartis, da diese Details auch innerhalb derselben Vertragskategorie variieren können.
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Nutzen Sie die Schaltfläche "Jetzt bewerben" auf dieser Seite — sie führt direkt zum Original-Inserat von Novartis unter novartis.wd3.myworkdayjobs.com, sodass Ihre Bewerbung direkt im Bewerbermanagementsystem des Arbeitgebers landet. Frontaliere Ticino sammelt oder leitet keine Bewerbungen selbst weiter.
