Founding Scientist - Antibody/Nanobody Drug Discovery — ETH Zürich
NouveauCHF 62 000 - 94 000
ETH Zürich · Basel (BS)
- Lieu
- Basel
- Contrat
- fixed-term
- Publié
- Hier
SalaireCHF 62 000 - 94 000
Vue d’ensemble du poste
Founding Scientist Antibody/Nanobody Drug Discovery
100%, Basel, fixed-term print Drucken
The group of Prof.
- Founding Scientist Antibody/Nanobody Drug Discovery
- 100%, Basel, fixed-term print Drucken
- include discovery, rigorous screening, and detailed characterization of novel protein binders,in an environment that treats translation, IP, and venture formation as part of the scientific discipline.
- Prior experience with protein engineering, display technologies (phage, yeast, or ribosome display), or cell-based assays is advantageous. Job description
Responsabilités principales
- include discovery, rigorous screening, and detailed characterization of novel protein binders,in an environment that treats translation, IP, and venture formation as part of the scientific discipline.
- Prior experience with protein engineering, display technologies (phage, yeast, or ribosome display), or cell-based assays is advantageous. Job description
- Experimentation: design and execute studies to develop and characterize novel antibodies and nanobodies.
- Assay development: create and validate cell-based / organoid assays to assess therapeutic potential and define the therapeutic window.
- Translational ownership: contribute hands-on to technology transfer, intellectual property (invention disclosures, FTO literature review), and the evolution of the therapeutic pipeline - including preparing materials for, and participating in, tech-transfer, partner, and investor discussions.
- Team: supervise and mentor a research technician, taking responsibility for a small team's output. Profile
- MSc or PhD in a relevant field, with a proven hands-on track record in the relevant workflows.
- Technical strength across: protein engineering and purification; display assays (phage, yeast, or ribosome);
- ELISA and BLI; flow cytometry, cell sorting, fluorescence microscopy; mammalian cell culture.
- Creativity and "out-of-the-box" thinking; ability to operate under pressure and deliver to timeline and budget.
Processus de candidature
- We welcome candidates with an MSc or PhD in biotechnology, molecular biology, protein science, or a related field, eager to apply their expertise to high-impact challenges.
- Optimization: apply molecular biology and protein engineering to enhance binders for affinity, specificity, and stability.
Détails supplémentaires
- Founding Scientist Antibody/Nanobody Drug Discovery
- 100%, Basel, fixed-term
- Andreas Moor (D-BSSE, ETH Zurich, located in Basel) is seeking an exceptional, entrepreneurially minded scientist to drive a colorectal-cancer metastasis-prevention antibody/nanobody program from discovery toward the clinic (start immediately or by arrangement). Your path: from fellowship to founding
- The intended path for the right person is to grow into a founding and scientific-leadership role in the venture as it takes shape. Project background
- Responsibilities include discovery, rigorous screening, and detailed characterization of novel protein binders,in an environment that treats translation, IP, and venture formation as part of the scientific discipline.
- Prior experience with protein engineering, display technologies (phage, yeast, or ribosome display), or cell-based assays is advantageous.
- Team: supervise and mentor a research technician, taking responsibility for a small team's output.
- Regulatory/drug-development exposure and animal-experimentation experience are a plus. This role is tailored for scientists who
- Value an environment where scientific inquiry meets strategic development (IP, spinoffs, and commercialization) and want hands-on exposure to it.
- An interdisciplinary environment alongside academic and industry experts, and real ownership of a program with translational and commercial potential.
Notes et contenu original
- Founding Scientist
- Antibody/Nanobody Drug Discovery
- Andreas Moor (D-BSSE, ETH Zurich, located in Basel) is seeking an exceptional, entrepreneurially minded scientist to drive a colorectal-cancer metastasis-prevention antibody/nanobody program from discovery toward the clinic (start immediately or by arrangement).
- Your path: from fellowship to founding
- The intended path for the right person is to grow into a founding and scientific-leadership role in the venture as it takes shape.
- Project background
- Job description
- Regulatory/drug-development exposure and animal-experimentation experience are a plus.
- This role is tailored for scientists who
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