Machine Learning Scientist — Roche
- Lieu
- Basel
- Contrat
- full-time
- Publié
- Aujourd'hui
Vue d’ensemble du poste
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
Processus de candidature
- We are seeking a (Senior) ML Scientist with deep expertise in modern machine learning to lead the development and application of next-generation AI technologies for designing DNA and RNA sequences for nucleic acid-based medicines.
- We work closely with stakeholders in Cell Therapy, Gene Therapy, and Vaccine Oncology on diverse projects, ranging from platform development for lab-in-the-loop refinement of sequence designs to lead optimization for portfolio projects.
- Representative work includes designing regulatory elements to confer cell-type-specific transcription and engineering synonymous coding sequences to enhance translational efficiency.
- As a Scientist / Senior Scientist, you will directly lead sequence design campaigns, translating biological questions into predictive and generative models, and driving iterative sequence optimization in close collaboration with wet-lab experimentalists. The Opportunity
- Build, train, and fine-tune machine learning algorithms to optimize nucleic acid-based medicines for active portfolio projects
- Design candidate sequence libraries for lab-in-the-loop optimization cycles, analyze experimental readouts (e.g., MPRA, NGS), and iteratively update designs
- Collaborate cross-functionally with wet-lab scientists and project leads to understand therapeutic constraints and tailor design algorithms accordingly
- Present technical findings, candidate designs, and model performance metrics to cross-functional team members and stakeholders
Détails supplémentaires
- Join Roche, where every voice matters.
- As a Scientist / Senior Scientist, you will directly lead sequence design campaigns, translating biological questions into predictive and generative models, and driving iterative sequence optimization in close collaboration with wet-lab experimentalists.
- Stay current with advancements in biological sequence modeling and nucleic acid therapeutics to bring state-of-the-art methods into our pipeline Contribute to scientific publications
- Excellent communication skills in English, with the ability to speak to both computational and experimental scientists
- Familiarity with high-throughput functional genomics data processing (e.g., MPRA, RNA-seq, ribosome profiling) About AI Biology & Translation (AIBT)
Notes et contenu original
- The Position
- The Opportunity
- Stay current with advancements in biological sequence modeling and nucleic acid therapeutics to bring state-of-the-art methods into our pipeline
- Contribute to scientific publications
- Who You Are
- Familiarity with high-throughput functional genomics data processing (e.g., MPRA, RNA-seq, ribosome profiling)
- About AI Biology & Translation (AIBT)
Questions sur cette offre
Quel salaire propose Roche pour ce poste ?
Roche indique CHF 62 000 - 94 000 bruts par an pour ce poste à Basel. Il s'agit du salaire publié dans l'annonce d'origine (ou, si l'employeur ne précise pas de montant, d'une estimation réaliste pour le rôle et le secteur) — le calculateur de ce site le convertit en net réel une fois l'impôt frontalier et les cotisations sociales appliqués.
Est-ce un poste à temps plein, et quel type de contrat propose Roche ?
Cette offre est un poste en temps plein. Le type de contrat affiché ici provient directement de l'annonce originale de l'employeur ; confirmez toujours les horaires exacts, le préavis et la durée d'essai avec Roche pendant le processus de candidature, ces détails pouvant varier même au sein de la même catégorie de contrat.
Ai-je besoin d'un permis de frontalier pour un poste dans le canton de Bâle ?
Les résidents UE/AELE domiciliés dans la zone frontalière du pays voisin du canton de Bâle peuvent demander un permis G ; l'employeur suisse le dépose auprès de l'office cantonal des migrations après signature du contrat. Les règles de zone frontalière et les délais varient selon le pays voisin et le canton — confirmez les détails auprès de l'office des migrations du canton de Bâle ou avec les RH pendant la candidature.
Comment postuler à ce poste chez Roche ?
Utilisez le bouton « Postuler maintenant » sur cette page — il renvoie directement à l'annonce originale de Roche sur roche.wd3.myworkdayjobs.com, votre candidature arrive donc directement dans le système de suivi des candidatures de l'employeur. Frontaliere Ticino ne collecte ni ne transmet lui-même les candidatures.
