Modelling and Simulations Scientist ( 2 year contract) — Roche
- Location
- Basel
- Contract
- full-time
- Posted
- 5 days ago
Role overview
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
Application process
- mechanistic insights to characterize drug accumulation and PK/PD relationships, including the impact of lysosomal trapping and binding dynamics.
- Extend modeling frameworks to areas such as combination therapies, antibody drug conjugates and antibiotic PK/PD.
- Design and deploy interactive tools, specifically using R and Shiny applications, to facilitate model exploration and guide internal decision-making.
- Leverage AI and Machine Learning to enhance predictive accuracy, automate data integration, and explore high-dimensional biological datasets.
- Perform rigorous parameter estimation through Bayesian methods and stochastic modeling techniques to extend deterministic frameworks.
- Communicate results quickly and effectively to project teams and senior management, ensuring M&S activities align with overall project goals and Roche standards. Who you are
- A PhD-level degree in natural sciences, mathematics, physical sciences, or engineering is required.
- Advanced programming skills in R and Python, with a proven ability to code quickly and with high rigor are required.
Additional details
- Join Roche, where every voice matters.
- You will design innovative quantitative approaches to predict clinical efficacy and safety, integrating pharmacological and toxicological data to ensure the optimal conduct of clinical studies.
- Your mission will be to conduct modelling and simulation activities at the project level through the development of quantitative physiology/mechanism-based and drug-disease models.
- Apply mechanistic insights to characterize drug accumulation and PK/PD relationships, including the impact of lysosomal trapping and binding dynamics.
- Communicate results quickly and effectively to project teams and senior management, ensuring M&S activities align with overall project goals and Roche standards.
- Growth mindset characterized by curiosity and a willingness to learn and go beyond standard solutions and methods.
Notes and original content
- The Position
- The Opportunity
- Who you are
Questions about this listing
What salary does Roche offer for this role?
Roche lists CHF 62'000 - 94'000 gross per year for this position in Basel. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Roche offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Roche during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Basel?
EU/EFTA residents living in the border zone of the country adjoining Canton Basel can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Basel's cantonal migration office or with HR during the application.
How do I apply for this position at Roche?
Use the "Apply now" button on this page — it links directly to Roche's original listing at roche.wd3.myworkdayjobs.com, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
