Postdoc – Drug development for Alzheimer's disease — Universität Zürich
- Location
- Zürich
- Contract
- full-time
- Posted
- 15 days ago
Role overview
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
Put your talent and skills to work with us.
- The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
- With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Main responsibilities
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- ELISA, Western blot) and to the careful documentation of experimental data. Anforderungen:
- PhD degree in biology, neuroscience, biomedicine or a related field.
- Experience in drug discovery in neurodegeneration is a plus.
- Hands-on experience with blood brain barrier research including setting up in vitro and in vivo models, quantitative analysis of drug penetration.
- Experience with LC-MS is a strong advantage.
- Solid histology experience: tissue sectioning (cryostat and/or microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal microscopy and quantitative analysis of large image batches (e.g.
- ImageJ/Fiji, QuPath).
- Experience with staining and quantifying brain pathology (amyloid-β plaques, tau, neuroinflammation markers) is a plus.
What the company offers
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Additional details
- Find out more about UZH as an employer!
- Responsibilities include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- ELISA, Western blot) and to the careful documentation of experimental data.
Notes and original content
- Anforderungen:
- Wir bieten:
Questions about this listing
What salary does Universität Zürich offer for this role?
Universität Zürich lists CHF 73'500 - 111'500 gross per year for this position in Zürich. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Universität Zürich offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Universität Zürich during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Zürich?
EU/EFTA residents living in the border zone of the country adjoining Canton Zürich can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Zürich's cantonal migration office or with HR during the application.
How do I apply for this position at Universität Zürich?
Use the "Apply now" button on this page — it links directly to Universität Zürich's original listing at jobs.uzh.ch, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
