Research Associate in In Vivo Genome Editing — Universität Zürich
- Location
- Zürich
- Contract
- full-time
- Posted
- 50 days ago
Role overview
Schwank Lab, Institute of Pharmacology, University of Zurich
Start of employment as soon as possible or upon agreement
- Schwank Lab, Institute of Pharmacology, University of Zurich
- Start of employment as soon as possible or upon agreement
- Your responsibilities
- Plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease required for the initiation of clinical trials.
- BSc or MSc in molecular biology, biotechnology, biomedicine, veterinary medicine, pharmaceutical sciences or a related discipline.
- Substantial hands-on experience conducting experiments with mice is essential.
Main responsibilities
- Your responsibilities
- Plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease required for the initiation of clinical trials.
- Administer genome-editing therapeutics and other test substances using relevant routes of delivery.
- Perform animal monitoring, blood and tissue collection, necropsies, organ harvesting and downstream sample processing.
- Perform molecular and cellular biology experiments, including mammalian cell culture, DNA and RNA isolation, PCR/qPCR, cloning and preparation of samples for sequencing.
- Analyse, interpret and document experimental results and contribute to the optimisation of experimental protocols.
- Maintain accurate records and ensure that all animal experiments are conducted in accordance with approved protocols and Swiss animal-welfare regulations.
- Collaborate closely with scientists, students and external project partners across several parallel research projects.
Key requirements
- BSc or MSc in molecular biology, biotechnology, biomedicine, veterinary medicine, pharmaceutical sciences or a related discipline.
- Substantial hands-on experience conducting experiments with mice is essential.
- Candidates should be confident in animal handling and in relevant experimental procedures such as dosing/injections, monitoring, blood sampling, tissue collection and necropsy.
- Strong practical experience in molecular and cellular biology (cloning, cell culture) and careful handling of biological samples.
- Experience with CRISPR genome editing, RNA therapeutics, lipid nanoparticles, viral vectors, liver biology or metabolic disease models is an advantage but not required.
- Ability to organise and conduct experiments independently, troubleshoot procedures and contribute effectively to multiple projects.
- A highly reliable, precise and collaborative working style, with strong attention to animal welfare and experimental documentation.
- Good written and spoken English. What we offer
- Find out more: https://www.uzh.ch/de/explore/work.html. Work-Life Balance
- Flexible working models (such as part-time positions, mobile working, job-sharing)
- Childcare at the kihz foundation of UZH and ETH More Learning and Development
- Wide range of continuing education courses of UZH and the Canton of Zurich
What the company offers
- Our employees benefit from a wide range of attractive offers.
Application process
- The Schwank Lab at the University of Zurich develops and translates next-generation genome-engineering technologies toward therapeutic applications.
- Our interdisciplinary research combines CRISPR-based genome editing, advanced delivery technologies, disease models, and preclinical studies, with major programmes in metabolic liver diseases, neurological disorders, and immune-cell engineering.
- A particular focus is the development of genome-editing therapies for urea cycle disorders, and we are currently advancing selected programmes toward clinical translation.
Additional details
- Good written and spoken English.
- Find out more: https://www.uzh.ch/de/explore/work.html.
- Childcare at the kihz foundation of UZH and ETH Learning and Development
- Language Center run jointly with ETH Zurich
- Food and drinks at reduced prices in the UZH cafeterias Lunch-Check-card with UZH contribution
- Special conditions on the Academic Sports Association ASVZ Free seasonal flu vaccinations
- Rest and relaxation at the quiet room in the university tower
- Digitalization: Hardware, software, mobile phone subscriptions Conditions of Employment Policies of the UZH
- Most UZH staff are employed according to public law International Services
- Support for people from outside Switzerland
Notes and original content
- Your profile
- What we offer
- Work-Life Balance
- Childcare at the kihz foundation of UZH and ETH
- Learning and Development
- Food and drinks at reduced prices in the UZH cafeterias
- Lunch-Check-card with UZH contribution
- Healthcare
- Special conditions on the Academic Sports Association ASVZ
- Free seasonal flu vaccinations
Questions about this listing
What salary does Universität Zürich offer for this role?
Universität Zürich lists CHF 91'500 - 128'000 gross per year for this position in Zürich. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Universität Zürich offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Universität Zürich during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Zürich?
EU/EFTA residents living in the border zone of the country adjoining Canton Zürich can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Zürich's cantonal migration office or with HR during the application.
How do I apply for this position at Universität Zürich?
Use the "Apply now" button on this page — it links directly to Universität Zürich's original listing at jobs.uzh.ch, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
