Director, Translational Medicine Expert (Neurodegeneration) — Novartis
NewCHF 85'500 - 129'500
Novartis · Basel (BS)
- Location
- Basel
- Contract
- full-time
- Posted
- 6 days ago
SalaryCHF 85'500 - 129'500
Role overview
Salary Range
CHF150,500.00
CHF279,500.00 Job Description Summary LI-Hybrid Internal job title: Director Location: Basel, Switzerland
- Salary Range:
- CHF150,500.00
- Key Responsibilities:
- Translational Strategy & Program Leadership
- & Rewards
- At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
Main responsibilities
- Key Responsibilities:
- Translational Strategy & Program Leadership
- Define and execute integrated translational strategies across neurodegeneration programs
- Lead translational components from preclinical → Phase 1/2 clinical studies
- Drive program progression through key decision gates (e.g., IND, TDP, IDPA)
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints Biomarker & Endpoint Leadership
- Collaborate with Biomarker Development colleagues toward development and validation of:
- Molecular biomarkers (tissue, blood, CSF where applicable)
- Functional endpoints (strength, mobility, disease-specific measures) Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support: Target engagement Disease modification Dose selection and PoC decisions
What the company offers
- & Rewards
- At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
- Expected Annual Base Salary Range for role:
- 150,500.00
- 279,500.00 CHF Annual
- The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
- In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
- The rewards of being part of our team go far beyond base pay and incentives.
- We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs.
- In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.
Application process
- Further details will be provided during the application process.
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.
- Read our brochure to learn more about our global total rewards offering:
- https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf
- A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process.
- Commitment to Diversity and Inclusion / EEO
- Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation
- Novartis is committed to working with and providing reasonable accommodation to all individuals.
Contacts
- position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information.
- Please include the job requisition number in your message. Skills Desired
- Clinical Trials, Data Analysis, Data Monitoring, Drug Development, Medical Research, People Management
Company and context
- Drive alignment between research, TM, and development organizations External Scientific Leadership Build and lead collaborations with: Academic KOLs
- Patient advocacy groups (critical in rare neuromuscular disease)
- Technology partners (imaging, omics platforms)
- Contribute to scientific strategy and external positioning of programs Patient-Centered Development
- Integrate the patient voice into translational and clinical strategies Advance: Meaningful functional endpoints Patient-relevant outcome measures
- Innovative trial approaches (e.g., decentralized models where feasible) Portfolio Contribution & Strategic Input Contribute to:
- Asset prioritization and portfolio strategy
- Competitive differentiation strategy (e.g., vs RNA or gene therapy competitors) Provide scientific input to: Business development / due diligence Indication expansion strategies Essential Requirements:
- MD, neurologists, clinical training in neurodegenerative diseases
- Experience in translational medicine, early clinical development, or experimental therapeutics.
Additional details
- Job Description Summary Internal job title: Director Location: Basel, Switzerland
- Support new and ongoing clinical research and clinical trials and ensure efficient and timely processing of confidentiality agreements and clinical agreements
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints Biomarker & Endpoint Leadership
- Functional endpoints (strength, mobility, disease-specific measures) Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support: Disease modification Dose selection and PoC decisions
- Drive early biomarker de‑risking , a key priority in neuromuscular programs Early Clinical Development (Phase 1/2)
- Co‑lead design and execution of early clinical studies Dose escalation strategy Exposure–response framework
- Ensure TM leadership within Clinical Trial Teams (CTTs) for: Execution oversight Data interpretation and decision-making Cross-Functional Leadership
- Serve as core Translational Medicine representative within global project teams Partner closely with: Clinical Development Biomarker Development Clinical Pharmacology (PKS) Preclinical Safety (PCS)
- Drive alignment between research, TM, and development organizations External Scientific Leadership Build and lead collaborations with:
Notes and original content
- CHF279,500.00
- Job Description Summary
- Internal job title: Director
- Location: Basel, Switzerland
- Job Description
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints
- Biomarker & Endpoint Leadership
- Functional endpoints (strength, mobility, disease-specific measures)
- Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support:
Questions about this listing
What salary does Novartis offer for this role?
Novartis lists CHF 85'500 - 129'500 gross per year for this position in Basel. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Novartis offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Novartis during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Basel?
EU/EFTA residents living in the border zone of the country adjoining Canton Basel can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Basel's cantonal migration office or with HR during the application.
How do I apply for this position at Novartis?
Use the "Apply now" button on this page — it links directly to Novartis's original listing at novartis.wd3.myworkdayjobs.com, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
