Principal Scientist - Mid/Large Scale Oligonucleotide Synthesis, xRNA Therapeutics — Novartis
- Località
- Basel
- Contratto
- full-time
- Pubblicato
- Ieri
Panoramica
Salary Range
CHF93,800.00
CHF174,200.00 Job Description Summary LI-Onsite Location: Basel, Switzerland Role Purpose:
- Salary Range:
- CHF93,800.00
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
Responsabilità principali
- Key Responsibilities
- Plan and execute medium- and large-scale solid-phase synthesis, purification, and analysis of chemically modified oligonucleotides (siRNAs, ASOs, and other emerging synthetic modalities) and conjugates to support our xRNA therapeutics portfolio.
- Mentor and lead a team of scientists specialized in oligonucleotide synthesis, purification, analysis, and conjugation at millimole scale.
- Collaborate with global discovery, development, and project teams to advance novel oligonucleotide chemistries and facilitate their successful transition from research into development.
- Identify and implement innovative technologies, workflows, and manufacturing approaches to enhance operational excellence, production capabilities, and turnaround times of siRNA, ASO and other oligonucleotide modalities supporting in vivo and preclinical studies.
Requisiti principali
- and Requirements:
- Ph.D. in Chemistry or related disciplines with a strong focus on oligonucleotide chemistry and synthesis.
- Minimum 2–3 years of industry experience and proven expertise in mid- large-scale oligonucleotide solid phase synthesis, purification, analysis, conjugation, and other related processes.
- Extensive experience operating and maintenance of AKTA Oligopilot/Oligosynt systems and AKTA Avant purification platforms, with strong proficiency in Unicorn software.
- Strong hands-on experience with process development, method optimization and scale-up strategies of oligonucleotides.
- Demonstrated leadership experience, including mentoring, and team management.
- Strong communication skills and ability to work effectively in a matrixed cross-functional global teams’ environment.
Cosa offre l’azienda
- & Rewards
- At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.
- Expected Annual Base Salary Range for role: 93,800.00
- 174,200.00 CHF Annual
- The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
- In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
- The rewards of being part of our team go far beyond base pay and incentives.
- We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs.
- In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. Read our broch
Processo di candidatura
- Communicate scientific findings and project updates effectively to internal and external stakeholders through presentations, technical reports, and patent applications.
- Maintain high-quality scientific documentation, including electronic laboratory notebooks (ELNs), experimental protocols, technical reports, and project summaries.
- Foster a culture of scientific excellence, collaboration, continuous learning, and solution-oriented problem solving.
Dettagli ulteriori
- Job Description Summary Location: Basel, Switzerland
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs. Qualifications and Requirements:
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.
Note e contenuto originale
- CHF174,200.00
- Job Description Summary
- Location: Basel, Switzerland
- Role Purpose:
- This role requires extensive collaboration within a multidisciplinary environment, bridging research and development to enable the discovery and advancement of innovative RNA therapies that address significant unmet medical needs.
- Job Description
- Qualifications and Requirements:
- Benefits & Rewards
- Read our broch
Domande frequenti su questo annuncio
Che stipendio offre Novartis per questa posizione?
Novartis indica CHF 85'500 - 129'500 lordi annui per questo ruolo a Basel. Questo è lo stipendio pubblicato nell'annuncio originale (o, quando il datore non specifica una cifra, una stima realistica per ruolo e settore) — il calcolatore di questo sito lo converte nel netto reale una volta applicate imposta da frontaliere e contributi sociali.
È un ruolo a tempo pieno, e che tipo di contratto offre Novartis?
Questo annuncio è una posizione a tempo pieno. Il tipo di contratto mostrato qui arriva direttamente dall'annuncio originale del datore di lavoro; conferma sempre orario esatto, preavviso e durata del periodo di prova con Novartis durante il colloquio, perché questi dettagli possono variare anche all'interno della stessa categoria contrattuale.
Serve un permesso da frontaliere per un ruolo nel canton Basilea?
I residenti UE/AELS nella zona di frontiera del paese confinante con il canton Basilea possono richiedere il Permesso G; il datore di lavoro svizzero lo presenta all'ufficio della migrazione di quel canton dopo la firma del contratto. Regole sulla zona di frontiera e tempi di lavorazione variano per paese confinante e canton — verifica i dettagli con l'ufficio della migrazione del canton Basilea o con HR durante il colloquio.
Come mi candido a questa posizione presso Novartis?
Usa il pulsante "Candidati ora" in questa pagina — rimanda direttamente all'annuncio originale di Novartis su novartis.wd3.myworkdayjobs.com, quindi la tua candidatura arriva direttamente nel sistema di gestione candidature del datore di lavoro. Frontaliere Ticino non raccoglie né inoltra candidature in proprio.
