Postdoc – Drug development for Alzheimer's disease — Universität Zürich
- Località
- Zürich
- Contratto
- full-time
- Pubblicato
- Ieri
Panoramica
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
Put your talent and skills to work with us.
- The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
- With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Responsabilità principali
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- ELISA, Western blot) and to the careful documentation of experimental data. Anforderungen:
- PhD degree in biology, neuroscience, biomedicine or a related field.
- Experience in drug discovery in neurodegeneration is a plus.
- Hands-on experience with blood brain barrier research including setting up in vitro and in vivo models, quantitative analysis of drug penetration.
- Experience with LC-MS is a strong advantage.
- Solid histology experience: tissue sectioning (cryostat and/or microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal microscopy and quantitative analysis of large image batches (e.g.
- ImageJ/Fiji, QuPath).
- Experience with staining and quantifying brain pathology (amyloid-β plaques, tau, neuroinflammation markers) is a plus.
Cosa offre l’azienda
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Dettagli ulteriori
- Find out more about UZH as an employer!
- Responsibilities include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- ELISA, Western blot) and to the careful documentation of experimental data.
Note e contenuto originale
- Anforderungen:
- Wir bieten:
Domande frequenti su questo annuncio
Che stipendio offre Universität Zürich per questa posizione?
Universität Zürich indica CHF 73'500 - 111'500 lordi annui per questo ruolo a Zürich. Questo è lo stipendio pubblicato nell'annuncio originale (o, quando il datore non specifica una cifra, una stima realistica per ruolo e settore) — il calcolatore di questo sito lo converte nel netto reale una volta applicate imposta da frontaliere e contributi sociali.
È un ruolo a tempo pieno, e che tipo di contratto offre Universität Zürich?
Questo annuncio è una posizione a tempo pieno. Il tipo di contratto mostrato qui arriva direttamente dall'annuncio originale del datore di lavoro; conferma sempre orario esatto, preavviso e durata del periodo di prova con Universität Zürich durante il colloquio, perché questi dettagli possono variare anche all'interno della stessa categoria contrattuale.
Serve un permesso da frontaliere per un ruolo nel canton Zurigo?
I residenti UE/AELS nella zona di frontiera del paese confinante con il canton Zurigo possono richiedere il Permesso G; il datore di lavoro svizzero lo presenta all'ufficio della migrazione di quel canton dopo la firma del contratto. Regole sulla zona di frontiera e tempi di lavorazione variano per paese confinante e canton — verifica i dettagli con l'ufficio della migrazione del canton Zurigo o con HR durante il colloquio.
Come mi candido a questa posizione presso Universität Zürich?
Usa il pulsante "Candidati ora" in questa pagina — rimanda direttamente all'annuncio originale di Universität Zürich su jobs.uzh.ch, quindi la tua candidatura arriva direttamente nel sistema di gestione candidature del datore di lavoro. Frontaliere Ticino non raccoglie né inoltra candidature in proprio.
