Postdoc – Drug development for Alzheimer's disease — Universität Zürich
- Lieu
- Zürich
- Contrat
- full-time
- Publié
- Hier
Vue d’ensemble du poste
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
Put your talent and skills to work with us.
- The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields.
- With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education.
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Responsabilités principales
- include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- The candidate will also contribute to standard biochemical read-outs (e.g.
- ELISA, Western blot) and to the careful documentation of experimental data. Anforderungen:
- PhD degree in biology, neuroscience, biomedicine or a related field.
- Experience in drug discovery in neurodegeneration is a plus.
- Hands-on experience with blood brain barrier research including setting up in vitro and in vivo models, quantitative analysis of drug penetration.
- Experience with LC-MS is a strong advantage.
- Solid histology experience: tissue sectioning (cryostat and/or microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal microscopy and quantitative analysis of large image batches (e.g.
- ImageJ/Fiji, QuPath).
- Experience with staining and quantifying brain pathology (amyloid-β plaques, tau, neuroinflammation markers) is a plus.
Ce que l’entreprise offre
- Our employees benefit from a wide range of attractive offers.
- Find out more: https://www.uzh.ch/de/explore/work.html.
Détails supplémentaires
- Find out more about UZH as an employer!
- Responsibilities include: (i) setting up in vitro and in vivo blood brain barrier models in the lab and test drug candidates in such models using ELISA or LC-MS etc; (ii) processing brain tissue for histological and biochemical assays, including sectioning (cryostat/microtome), immunohistochemistry and immunofluorescence staining, fluorescence/confocal imaging, quantitative large-batch image analysis, ELISA and western blot assays for brain homogenates; and (iii) supporting cell-based assays, including mammalian cell culture, microglial phagocytosis assays and flow cytometry (FACS).
- ELISA, Western blot) and to the careful documentation of experimental data.
Notes et contenu original
- Anforderungen:
- Wir bieten:
Questions sur cette offre
Quel salaire propose Universität Zürich pour ce poste ?
Universität Zürich indique CHF 73 500 - 111 500 bruts par an pour ce poste à Zürich. Il s'agit du salaire publié dans l'annonce d'origine (ou, si l'employeur ne précise pas de montant, d'une estimation réaliste pour le rôle et le secteur) — le calculateur de ce site le convertit en net réel une fois l'impôt frontalier et les cotisations sociales appliqués.
Est-ce un poste à temps plein, et quel type de contrat propose Universität Zürich ?
Cette offre est un poste en temps plein. Le type de contrat affiché ici provient directement de l'annonce originale de l'employeur ; confirmez toujours les horaires exacts, le préavis et la durée d'essai avec Universität Zürich pendant le processus de candidature, ces détails pouvant varier même au sein de la même catégorie de contrat.
Ai-je besoin d'un permis de frontalier pour un poste dans le canton de Zurich ?
Les résidents UE/AELE domiciliés dans la zone frontalière du pays voisin du canton de Zurich peuvent demander un permis G ; l'employeur suisse le dépose auprès de l'office cantonal des migrations après signature du contrat. Les règles de zone frontalière et les délais varient selon le pays voisin et le canton — confirmez les détails auprès de l'office des migrations du canton de Zurich ou avec les RH pendant la candidature.
Comment postuler à ce poste chez Universität Zürich ?
Utilisez le bouton « Postuler maintenant » sur cette page — il renvoie directement à l'annonce originale de Universität Zürich sur jobs.uzh.ch, votre candidature arrive donc directement dans le système de suivi des candidatures de l'employeur. Frontaliere Ticino ne collecte ni ne transmet lui-même les candidatures.
