Staff Engineer, Drug Substance, MSAT — Vaxcyte
NewCHF 60'500 - 91'500
Vaxcyte · Visp (VS)
- Location
- Visp
- Contract
- full-time
- Posted
- Yesterday
SalaryCHF 60'500 - 91'500
Role overview
Join our Mission to Protect Humankind!
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked.
Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning.
- Join our Mission to Protect Humankind!
- Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked.
Application process
- Drive continuous improvement and change management in DS manufacturing processes through technological innovation and application of first principles in process engineering.
- Support the process to select new CMOs and suppliers.
- Leverage literature, industry/regulatory guidance, and practical experience to perform work and influence CMC strategies.
- Recommend and implement new technology that advances knowledge and productivity within the department.
- Drive continuous improvement.
- Author and review technical reports, manufacturing documents, regulatory submissions, and publications.
- Present at department, project team, and senior management meetings.
- May present externally at scientific conferences.
Company and context
- The incumbent will support the conjugation manufacturing operations from commercial readiness through PPQ and ongoing commercial production, onsite at contract manufacturing organizations (CMO), with the primary responsibility to provide technical and operational support of manufacturing operations that ensure robust and efficient manufacturing processes.
- This position will primarily be located in Visp, Switzerland.
- This position will require the candidate to manage the highly complex conjugation manufacturing processes for Vaxcyte’s vaccine portfolio.
- This is an exciting opportunity to join an outstanding team, with a mission to support late-stage clinical manufacture, launch, and commercial operations for the PCV franchise.
- The successful candidate will have the following skills and qualities:
- A skilled process engineer with expertise in: Molecule activation and bioconjugation (e.g., activation chemistries, conjugation reaction kinetics, in-process controls, and common side reactions/impurities)
- Strong quantitative skills: trend and multivariate analysis of process and analytical data to support continued process verification (CPV), deviation investigations, and process characterization (e.g., DOE).
- An exceptional team player who works seamlessly with others, speaks up, and remains focused on achieving the best results to attain company goals.
- The ability to analyze data and communicate conclusions, decisions and recommendations concisely to key stakeholders.
- A strong sense of ownership and accountability; commitment to Vaxcyte’s mission of protecting humankind. Essential Functions:
Additional details
- MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
- A strong sense of ownership and accountability; commitment to Vaxcyte’s mission of protecting humankind. Essential Functions:
- Support the CMOs during inspections of health authorities where necessary and ensure proper follow-up of any potential observation or recommendation.
- Reports to: Associate Director, MSAT Bioconjugates Location: Visp, Switzerland Work Arrangement: Onsite
- The compensation package will be competitive and includes an equity component.
Notes and original content
- A strong sense of ownership and accountability; commitment to Vaxcyte’s mission of protecting humankind.
- Essential Functions:
- Requirements:
- Reports to: Associate Director, MSAT Bioconjugates
- Location: Visp, Switzerland
- Work Arrangement: Onsite
- Compensation:
- Relocation:
