Modelling and Simulations Scientist ( 2 year contract) — Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position At Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives, and we are fearless in both decision and action. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. Roche Pharma Research and Early Development (pRED) translates extraordinary science into medical innovation through a diversity of technologies and talent. The translational Modelling and Simulation (tM&S) capability, part of the Predictive Modeling (PM) Chapter, aims to enhance understanding of disease biology and inform the selection of the right molecules for development. We are looking for a scientist to support early research and development with mathematical modeling. This role requires a candidate with a strong mathematical background and a pragmatic approach to drug development. You will design innovative quantitative approaches to predict clinical efficacy and safety, integrating pharmacological and toxicological data to ensure the optimal conduct of clinical studies. The Opportunity Your mission will be to conduct modelling and simulation activities at the project level through the development of quantitative physiology/mechanism-based and drug-disease models. You will: • Develop multi-scale models for PK, efficacy, and toxicology by integrating experimental data (in vitro, in vivo, and omics) and literature-based evidence. • Build complex quantitative systems pharmaco