Scientist, Cell Engineering and Phenotypic Screening Models — Roche
- Location
- Basel
- Contract
- full-time
- Posted
- Yesterday
Role overview
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
- Key responsibilities include:
- Model Innovation: Independently design, engineer, validate, and optimize disease-relevant cellular models at scale to enable phenotypic screening and small molecule drug discovery.
Main responsibilities
- Key responsibilities include:
- Model Innovation: Independently design, engineer, validate, and optimize disease-relevant cellular models at scale to enable phenotypic screening and small molecule drug discovery.
- Pipeline Integration: Translate complex cellular models into scalable, reproducible, screening-compatible workflows for high-content imaging and phenotypic screening.
- Cross-Functional Collaboration: Partner actively across therapeutic areas, automation, data analysis, and chemistry teams to interpret results, present data, and support project decisions.
- Culture Contribution: Actively cultivate an inclusive, collaborative, and curious team environment focused on pushing scientific boundaries. Who You Are
- You are a curious, highly motivated scientist who thrives on solving complex biological challenges.
- Education & Experience: A PhD in cell biology, molecular biology, or a closely related scientific discipline.
- Postdoctoral or industry research experience is a plus but not required.
- Cell Culture Expertise: Strong hands-on experience in advanced cell culture techniques, including iPSC differentiation and larger-scale cell culture.
- Advanced Genome Editing: Extensive practical experience in cell engineering, particularly CRISPR/Cas-based genome editing, stable cell line generation, clonal isolation, genotyping, and validation using Next-Generation Sequencing (NGS).
Application process
- Advanced Engineering: Apply diverse cell engineering approaches, including CRISPR/Cas technologies, vector design, reporter systems, and stable cell line generation, to build robust assay systems.
- You bring a collaborative mindset and are eager to apply your technical expertise to discover life-changing treatments. To thrive in this role, you bring:
Company and context
- In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.
- At pRED, we are united by our mission to transform science into medicines.
- Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
- Therapeutic Modalities (TMo) organization, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact. The Opportunity
- Joining Small Molecule Research Discovery within Therapeutic Modalities, you will work within a highly engaged, cross-functional team bridging cell biology, automation, and multiple therapeutic areas.
- In this role, you drive innovation through strong commitment to lab science by developing the foundational cellular models that power our drug discovery pipeline.
Additional details
- Join Roche, where every voice matters.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.
- Culture Contribution: Actively cultivate an inclusive, collaborative, and curious team environment focused on pushing scientific boundaries.
- You bring a collaborative mindset and are eager to apply your technical expertise to discover life-changing treatments. To thrive in this role, you bring:
- Expertise in high-content data analysis, image processing pipelines, or multiparametric data evaluation is a plus.
Notes and original content
- The Position
- The Opportunity
- Who You Are
- You bring a collaborative mindset and are eager to apply your technical expertise to discover life-changing treatments.
- To thrive in this role, you bring:
- Communication & Mi
Questions about this listing
What salary does Roche offer for this role?
Roche lists CHF 62'000 - 94'000 gross per year for this position in Basel. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Roche offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Roche during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Basel?
EU/EFTA residents living in the border zone of the country adjoining Canton Basel can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Basel's cantonal migration office or with HR during the application.
How do I apply for this position at Roche?
Use the "Apply now" button on this page — it links directly to Roche's original listing at roche.wd3.myworkdayjobs.com, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
