Research Associate In Cellular Assay Development — Roche
- Location
- Basel
- Contract
- full-time
- Posted
- Yesterday
Role overview
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
- Your key responsibilities include:
- Developing, optimizing, and validating robust cell-based functional assays—including complex 3D models—using technologies such as HTRF, AlphaLISA, Luminescence, and High-Content Imaging.
- and skills:
- Master’s degree in Cell Biology, Molecular Biology, or a closely related scientific discipline.
Main responsibilities
- Your key responsibilities include:
- Developing, optimizing, and validating robust cell-based functional assays—including complex 3D models—using technologies such as HTRF, AlphaLISA, Luminescence, and High-Content Imaging.
- Miniaturizing cellular assays into high-density plate formats (384-well and 1536-well plates), optimizing performance parameters such as Z’-factor and signal-to-background ratio.
- Maintaining, characterizing, and performing quality control on a wide range of mammalian cell lines, including primary cells, continuous lines, and induced pluripotent stem cells (iPSCs).
- Partnering closely with the High-Throughput Screening and Profiling team to seamlessly transfer new assays onto integrated robotic systems.
- Running routine cellular assays to generate high-quality data supporting structure-activity relationship (SAR) studies for portfolio projects.
- Analyzing complex screening datasets using modern scientific tools (e.g., Genedata Screener,
- Spotfire) and documenting workflows meticulously in Electronic Lab Notebooks (ELN).
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups. Who You Are
- You are a curious, highly motivated scientist who thrives on solving complex biological challenges.
Key requirements
- and skills:
- Master’s degree in Cell Biology, Molecular Biology, or a closely related scientific discipline.
- 5+ years of relevant industry research experience focused on advanced cell culture and cell-based assay development.
- Demonstrated experience in miniaturizing assay workflows into 384- and 1536-well plate formats and utilizing automated liquid-handling systems.
- Strong proficiency in data analysis, statistical evaluation, and presenting scientific findings clearly to multidisciplinary teams.
- Fluency in English with strong interpersonal and communication skills.
- Flexibility and a resourceful problem-solving approach tailored to a dynamic lab environment.
- Nice to have: Hands-on experience with iPSC differentiation, 3D
Application process
- You bring a collaborative mindset, value diverse perspectives, and are eager to apply your expertise to discover life-changing treatments.
Company and context
- In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs.
- At pRED, we are united by our mission to transform science into medicines.
- Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
- Therapeutic Modalities (TMo) organization, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact. The Opportunity
- Joining Small Molecule Research Discovery within Therapeutic Modalities, you will work within a highly engaged, cross-functional team bridging cell biology, automation, and multiple therapeutic areas.
- In this role, you drive innovation through strong commitment to lab science by developing the foundational cellular models that power our drug discovery pipeline.
Additional details
- Join Roche, where every voice matters.
- By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups. Qualifications and skills:
Notes and original content
- The Position
- The Opportunity
- Serving as the primary cellular assay expert on multidisciplinary project teams, sharing insights across chemistry, High-Throughput Screening and Profiling, and therapeutic area groups.
- Who You Are
- Qualifications and skills:
Questions about this listing
What salary does Roche offer for this role?
Roche lists CHF 64'500 - 110'000 gross per year for this position in Basel. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Roche offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Roche during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Basel?
EU/EFTA residents living in the border zone of the country adjoining Canton Basel can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Basel's cantonal migration office or with HR during the application.
How do I apply for this position at Roche?
Use the "Apply now" button on this page — it links directly to Roche's original listing at roche.wd3.myworkdayjobs.com, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
