Global Head of Clinical Safety, Development and Marketed Medicines — Roche
- Location
- Basel
- Contract
- full-time
- Posted
- 2 days ago
Role overview
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
- Primary Responsibilities and Accountabilities Strategic Safety & Portfolio Delivery
- Direct the global strategy for proactive safety and risk management, aligning asset strategies with Target Product Profiles (TPPs) and Clinical Development Plans (CDPs).
Main responsibilities
- Primary Responsibilities and Accountabilities Strategic Safety & Portfolio Delivery
- Direct the global strategy for proactive safety and risk management, aligning asset strategies with Target Product Profiles (TPPs) and Clinical Development Plans (CDPs).
- Oversee early-to-late phase safety transitions, optimizing risk minimization strategies, personalized safety approaches, and translational safety inputs.
- Ensure effective representation and input on key governance bodies (e.g., Drug Safety Committee, Translational Safety Committee, Development Boards) and lead safety due diligence for portfolio decisions. Strategic Partnering & Escalation
- Collaborate closely with PDS peers (e.g., Portfolio Clinical Safety, PV & Scientific Development) and broader R&D groups to drive agile, scientific safety approaches.
- Empower functional experts to lead cross-functional safety initiatives with senior Roche stakeholders and Board chairs.
- Serve as the global point of escalation for critical, complex, or ambiguous portfolio-level safety issues. Strategic Resourcing & Capability Building
- Partner with PDS leadership to strategically manage capacity, talent deployment, and resource allocation across EDS and LMMS, and Clinical Safety more broadly, based on portfolio priorities. Drive capability development ini
Company and context
- The Product Development Safety (PDS) organization delivers patient-centric scientific safety solutions that build trust and create value for society, leading to smarter safety design and decision-making activities throughout the drug lifecycle.
- PDS sustains Pharmacovigilance (PV) system compliance and quality, in order to foster trust and drive efficiency, while also innovating and improving the capabilities that address the evolving priorities of our enterprise and wider healthcare ecosystem.
- We shape clinical safety, risk management approaches, and safety decisions across the entire asset lifecycle-from early development prior to pivotal stage development through to marketed molecules.
- In close collaboration with cross-functional stakeholders, we drive and implement scientific safety strategies to optimize patient risk management at every stage of molecule maturity. The Opportunity
- The Global Head of Clinical Safety, Development and Marketed Medicines provides global strategic leadership across early development (pre-IND through early clinical phases) and late-stage/marketed assets (pivotal trials through post-loss-of-exclusivity).
- As a core member of the PD Safety Leadership Team, this role shapes Roche’s end-to-end clinical safety and risk management strategies across all therapeutic areas and modalities (medicinal products, devices, ATMPs).
- This role leads a team of 9 therapeutic area leaders and oversees an organization of approximately 60 physicians/scientists, who act as the strategic safety leads for all of Roche's development and on-market portfolio.
- Additionally, the job holder partners closely with the Global Head of Portfolio Clinical Safety, who oversees the safety scientists that support the strategic safety leads, ensuring that the scientific safety needs of all programs are appropriately met.
- By taking an 'entire lifecycle view', this role ensures seamless knowledge transfer across phase transitions, drives cross-functional alignment with R&D partners (e.g., gRED, pRED, CICoR, PD), and acts as a key point of escalation for portfolio-level safety decisions and governance (e.g., Drug Safety Committee, Development Boards).
Additional details
- Join Roche, where every voice matters.
- In close collaboration with cross-functional stakeholders, we drive and implement scientific safety strategies to optimize patient risk management at every stage of molecule maturity.
- Primary Responsibilities and Accountabilities Strategic Safety & Portfolio Delivery
- Ensure effective representation and input on key governance bodies (e.g., Drug Safety Committee, Translational Safety Committee, Development Boards) and lead safety due diligence for portfolio decisions. Strategic Partnering & Escalation
- Serve as the global point of escalation for critical, complex, or ambiguous portfolio-level safety issues. Strategic Resourcing & Capability Building
- Partner with PDS leadership to strategically manage capacity, talent deployment, and resource allocation across EDS and LMMS, and Clinical Safety more broadly, based on portfolio priorities. Drive capability development ini
Notes and original content
- The Position
- Who We Are
- The Opportunity
- Primary Responsibilities and Accountabilities
- Strategic Safety & Portfolio Delivery
- Ensure effective representation and input on key governance bodies (e.g., Drug Safety Committee, Translational Safety Committee, Development Boards) and lead safety due diligence for portfolio decisions.
- Strategic Partnering & Escalation
- Serve as the global point of escalation for critical, complex, or ambiguous portfolio-level safety issues.
- Strategic Resourcing & Capability Building
- Partner with PDS leadership to strategically manage capacity, talent deployment, and resource allocation across EDS and LMMS, and Clinical Safety more broadly, based on portfolio priorities.
Questions about this listing
What salary does Roche offer for this role?
Roche lists CHF 99'500 - 169'500 gross per year for this position in Basel. This is the salary published in the original listing (or, when the employer omits a figure, a realistic estimate for the role and sector) — the calculator on this site converts it to your actual net take-home once cross-border tax and social contributions are applied.
Is this a full-time role, and what type of contract does Roche offer?
This listing is a full-time position. The contract type shown here comes directly from the employer's original posting; always confirm exact hours, notice period and probation length with Roche during the application process, since these details can vary by role even within the same contract category.
Do I need a cross-border work permit for a role in Basel?
EU/EFTA residents living in the border zone of the country adjoining Canton Basel can apply for a G permit; the Swiss employer files it with that canton's migration office after the contract is signed. Border-zone rules and processing times vary by neighbouring country and canton, so confirm the specifics with Basel's cantonal migration office or with HR during the application.
How do I apply for this position at Roche?
Use the "Apply now" button on this page — it links directly to Roche's original listing at roche.wd3.myworkdayjobs.com, so your application goes straight to the employer's own applicant-tracking system. Frontaliere Ticino does not collect or forward applications itself.
