Machine Learning Scientist — Roche
- Località
- Basel
- Contratto
- full-time
- Pubblicato
- Oggi
Panoramica
At Roche you can show up as yourself, embraced for the unique qualities you bring.
Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.
- At Roche you can show up as yourself, embraced for the unique qualities you bring.
- Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally.
Processo di candidatura
- We are seeking a (Senior) ML Scientist with deep expertise in modern machine learning to lead the development and application of next-generation AI technologies for designing DNA and RNA sequences for nucleic acid-based medicines.
- We work closely with stakeholders in Cell Therapy, Gene Therapy, and Vaccine Oncology on diverse projects, ranging from platform development for lab-in-the-loop refinement of sequence designs to lead optimization for portfolio projects.
- Representative work includes designing regulatory elements to confer cell-type-specific transcription and engineering synonymous coding sequences to enhance translational efficiency.
- As a Scientist / Senior Scientist, you will directly lead sequence design campaigns, translating biological questions into predictive and generative models, and driving iterative sequence optimization in close collaboration with wet-lab experimentalists. The Opportunity
- Build, train, and fine-tune machine learning algorithms to optimize nucleic acid-based medicines for active portfolio projects
- Design candidate sequence libraries for lab-in-the-loop optimization cycles, analyze experimental readouts (e.g., MPRA, NGS), and iteratively update designs
- Collaborate cross-functionally with wet-lab scientists and project leads to understand therapeutic constraints and tailor design algorithms accordingly
- Present technical findings, candidate designs, and model performance metrics to cross-functional team members and stakeholders
Dettagli ulteriori
- Join Roche, where every voice matters.
- As a Scientist / Senior Scientist, you will directly lead sequence design campaigns, translating biological questions into predictive and generative models, and driving iterative sequence optimization in close collaboration with wet-lab experimentalists.
- Stay current with advancements in biological sequence modeling and nucleic acid therapeutics to bring state-of-the-art methods into our pipeline Contribute to scientific publications
- Excellent communication skills in English, with the ability to speak to both computational and experimental scientists
- Familiarity with high-throughput functional genomics data processing (e.g., MPRA, RNA-seq, ribosome profiling) About AI Biology & Translation (AIBT)
Note e contenuto originale
- The Position
- The Opportunity
- Stay current with advancements in biological sequence modeling and nucleic acid therapeutics to bring state-of-the-art methods into our pipeline
- Contribute to scientific publications
- Who You Are
- Familiarity with high-throughput functional genomics data processing (e.g., MPRA, RNA-seq, ribosome profiling)
- About AI Biology & Translation (AIBT)
Domande frequenti su questo annuncio
Che stipendio offre Roche per questa posizione?
Roche indica CHF 62'000 - 94'000 lordi annui per questo ruolo a Basel. Questo è lo stipendio pubblicato nell'annuncio originale (o, quando il datore non specifica una cifra, una stima realistica per ruolo e settore) — il calcolatore di questo sito lo converte nel netto reale una volta applicate imposta da frontaliere e contributi sociali.
È un ruolo a tempo pieno, e che tipo di contratto offre Roche?
Questo annuncio è una posizione a tempo pieno. Il tipo di contratto mostrato qui arriva direttamente dall'annuncio originale del datore di lavoro; conferma sempre orario esatto, preavviso e durata del periodo di prova con Roche durante il colloquio, perché questi dettagli possono variare anche all'interno della stessa categoria contrattuale.
Serve un permesso da frontaliere per un ruolo nel canton Basilea?
I residenti UE/AELS nella zona di frontiera del paese confinante con il canton Basilea possono richiedere il Permesso G; il datore di lavoro svizzero lo presenta all'ufficio della migrazione di quel canton dopo la firma del contratto. Regole sulla zona di frontiera e tempi di lavorazione variano per paese confinante e canton — verifica i dettagli con l'ufficio della migrazione del canton Basilea o con HR durante il colloquio.
Come mi candido a questa posizione presso Roche?
Usa il pulsante "Candidati ora" in questa pagina — rimanda direttamente all'annuncio originale di Roche su roche.wd3.myworkdayjobs.com, quindi la tua candidatura arriva direttamente nel sistema di gestione candidature del datore di lavoro. Frontaliere Ticino non raccoglie né inoltra candidature in proprio.
