Site Manager - China Supplier & CDMO Operations — Roche

Descrizione completa

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position About the Role Roche's External Manufacturing organization is seeking an experienced Site Manager to lead China-based supplier and CDMO relationships and serve as the primary external manufacturing contact for China-originated product development and due diligence activities. Based at our Shanghai facilities, you will manage a diverse supplier portfolio spanning small molecules, peptides, and biologics (including E. coli-derived products). You will own the end-to-end relationship with China CDMOs across the product lifecycle—from supplier selection and technology transfer (where appropriate) through commercial supply and decommissioning—while ensuring full alignment with Roche's quality, compliance, and operational standards. Key Responsibilities Supplier Selection & Partnership Development

• Lead due diligence activities to evaluate CDMO capacity, GMP compliance, and strategic fit
• Define outsourcing requirements, manage RFP processes, and drive supplier selection in collaboration with cross-functional teams
• Establish governance frameworks and long-term relationships with strategic CDMO partners
• Negotiate contracts and commercial terms in alignment with business objectives Operational & Project Management
• Manage technology transfers, product launches, and development activities across multiple CDMOs
• Lead cross-functional project and joint management teams spanning development, quality, supply chain, and regulatory functions
• Monitor production performance, identify supply constraints, and drive continuous improvement initiatives
• Own budgets for prelaunch activities, commercial production, and technical projects Quality, Compliance & Risk Management
• Ensure GMP, quality, safety, and environmental standards are consistently met across all partner sites
• Coordinate corporate audits and drive implementation of corrective actions
• Perform regular risk reviews and define mitigation strategies with partners
• Maintain full regulatory and business compliance throughout all supplier relationships Strategic Collaboration
• Partner with internal stakeholders ( Development, Technical and Business product Teams, procurement, regulatory, quality, Finance) to align supplier strategies with product development timelines and commercial objectives
• Serve as the primary relationship manager and escalation point for China CDMO matters
• Contribute to cost reduction initiatives and supply chain optimization across the product lifecycle Who You Are Experience & Education
• 10+ years in operations, manufacturing within a GMP-regulated pharmaceutical environment
• 5+ years managing complex, cross-functional projects or operational units
• 3+ years leading direct reports or equivalent experience in matrix/cross-functional team leadership
• Bachelor's degree in Engineering, Chemistry, Life Sciences, or related field (MBA or advanced degree preferred)
• Demonstrated experience with contract manufacturers, drug substance (DS) and drug product (DP) development, and GMP compliance Core Competencies
• Strategic agility: Balance long-term partnerships with adaptability to changing business needs
• Results-driven: Deliver superior outcomes by empowering teams and maintaining focus on key priorities
• Leadership & collaboration: Influence at all organizational levels with strong communication and interpersonal skills
• Business acumen: Understand cost-of-goods calculations and drive price negotiations
• Integrity & accountability: Upho