Direttore, Translational Medicine Expert (Neurodegeneration) — Novartis
- Località
- Basel
- Contratto
- full-time
- Pubblicato
- Oggi
Panoramica
Salary Range
CHF150,500.00
CHF279,500.00 Job Description Summary LI-Hybrid Internal job title: Director Location: Basel, Switzerland
- Salary Range:
- CHF150,500.00
- Key Responsibilities:
- Translational Strategy & Program Leadership
Responsabilità principali
- Key Responsibilities:
- Translational Strategy & Program Leadership
- Define and execute integrated translational strategies across neurodegeneration programs
- Lead translational components from preclinical → Phase 1/2 clinical studies
- Drive program progression through key decision gates (e.g., IND, TDP, IDPA)
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints Biomarker & Endpoint Leadership
- Collaborate with Biomarker Development colleagues toward development and validation of:
- Molecular biomarkers (tissue, blood, CSF where applicable)
- Functional endpoints (strength, mobility, disease-specific measures) Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support: Target engagement Disease modification Dose selection and PoC decisions
Azienda e contesto
- Drive alignment between research, TM, and development organizations External Scientific Leadership Build and lead collaborations with: Academic KOLs
- Patient advocacy groups (critical in rare neuromuscular disease)
- Technology partners (imaging, omics platforms)
- Contribute to scientific strategy and external positioning of programs Patient-Centered Development
- Integrate the patient voice into translational and clinical strategies Advance: Meaningful functional endpoints Patient-relevant outcome measures
- Innovative trial approaches (e.g., decentralized models where feasible) Portfolio Contribution & Strategic Input Contribute to:
- Asset prioritization and portfolio strategy
- Competitive differentiation strategy (e.g., vs RNA or gene therapy competitors) Provide scientific input to: Business development / due diligence Indication expansion strategies Essential Requirements:
- MD, neurologists, clinical training in neurodegenerative diseases
- Experience in translational medicine, early clinical development, or experimental therapeutics.
Dettagli ulteriori
- Job Description Summary Internal job title: Director Location: Basel, Switzerland
- Support new and ongoing clinical research and clinical trials and ensure efficient and timely processing of confidentiality agreements and clinical agreements
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints Biomarker & Endpoint Leadership
- Functional endpoints (strength, mobility, disease-specific measures) Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support: Disease modification Dose selection and PoC decisions
- Drive early biomarker de‑risking , a key priority in neuromuscular programs Early Clinical Development (Phase 1/2)
- Co‑lead design and execution of early clinical studies Dose escalation strategy Exposure–response framework
- Ensure TM leadership within Clinical Trial Teams (CTTs) for: Execution oversight Data interpretation and decision-making Cross-Functional Leadership
- Serve as core Translational Medicine representative within global project teams Partner closely with: Clinical Development Biomarker Development Clinical Pharmacology (PKS) Preclinical Safety (PCS)
- Drive alignment between research, TM, and development organizations External Scientific Leadership Build and lead collaborations with:
Note e contenuto originale
- CHF279,500.00
- Job Description Summary
- Internal job title: Director
- Location: Basel, Switzerland
- Job Description
- Ensure strong mechanistic linkage between target biology, biomarkers, and clinical endpoints
- Biomarker & Endpoint Leadership
- Functional endpoints (strength, mobility, disease-specific measures)
- Patient-reported outcomes (PROs)
- Establishing quantitative biomarkers to support:
Domande frequenti su questo annuncio
Che stipendio offre Novartis per questa posizione?
Novartis indica CHF 85'500 - 129'500 lordi annui per questo ruolo a Basel. Questo è lo stipendio pubblicato nell'annuncio originale (o, quando il datore non specifica una cifra, una stima realistica per ruolo e settore) — il calcolatore di questo sito lo converte nel netto reale una volta applicate imposta da frontaliere e contributi sociali.
È un ruolo a tempo pieno, e che tipo di contratto offre Novartis?
Questo annuncio è una posizione a tempo pieno. Il tipo di contratto mostrato qui arriva direttamente dall'annuncio originale del datore di lavoro; conferma sempre orario esatto, preavviso e durata del periodo di prova con Novartis durante il colloquio, perché questi dettagli possono variare anche all'interno della stessa categoria contrattuale.
Serve un permesso da frontaliere per un ruolo nel canton Basilea?
I residenti UE/AELS nella zona di frontiera del paese confinante con il canton Basilea possono richiedere il Permesso G; il datore di lavoro svizzero lo presenta all'ufficio della migrazione di quel canton dopo la firma del contratto. Regole sulla zona di frontiera e tempi di lavorazione variano per paese confinante e canton — verifica i dettagli con l'ufficio della migrazione del canton Basilea o con HR durante il colloquio.
Come mi candido a questa posizione presso Novartis?
Usa il pulsante "Candidati ora" in questa pagina — rimanda direttamente all'annuncio originale di Novartis su novartis.wd3.myworkdayjobs.com, quindi la tua candidatura arriva direttamente nel sistema di gestione candidature del datore di lavoro. Frontaliere Ticino non raccoglie né inoltra candidature in proprio.
