Ricerca Associate in In Vivo Genome Editing — Universität Zürich
- Località
- Zürich
- Contratto
- full-time
- Pubblicato
- 49 giorni fa
Panoramica
Schwank Lab, Institute of Pharmacology, University of Zurich
Start of employment as soon as possible or upon agreement
- Schwank Lab, Institute of Pharmacology, University of Zurich
- Start of employment as soon as possible or upon agreement
- Your responsibilities
- Plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease required for the initiation of clinical trials.
- BSc or MSc in molecular biology, biotechnology, biomedicine, veterinary medicine, pharmaceutical sciences or a related discipline.
- Substantial hands-on experience conducting experiments with mice is essential.
Responsabilità principali
- Your responsibilities
- Plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease required for the initiation of clinical trials.
- Administer genome-editing therapeutics and other test substances using relevant routes of delivery.
- Perform animal monitoring, blood and tissue collection, necropsies, organ harvesting and downstream sample processing.
- Perform molecular and cellular biology experiments, including mammalian cell culture, DNA and RNA isolation, PCR/qPCR, cloning and preparation of samples for sequencing.
- Analyse, interpret and document experimental results and contribute to the optimisation of experimental protocols.
- Maintain accurate records and ensure that all animal experiments are conducted in accordance with approved protocols and Swiss animal-welfare regulations.
- Collaborate closely with scientists, students and external project partners across several parallel research projects.
Requisiti principali
- BSc or MSc in molecular biology, biotechnology, biomedicine, veterinary medicine, pharmaceutical sciences or a related discipline.
- Substantial hands-on experience conducting experiments with mice is essential.
- Candidates should be confident in animal handling and in relevant experimental procedures such as dosing/injections, monitoring, blood sampling, tissue collection and necropsy.
- Strong practical experience in molecular and cellular biology (cloning, cell culture) and careful handling of biological samples.
- Experience with CRISPR genome editing, RNA therapeutics, lipid nanoparticles, viral vectors, liver biology or metabolic disease models is an advantage but not required.
- Ability to organise and conduct experiments independently, troubleshoot procedures and contribute effectively to multiple projects.
- A highly reliable, precise and collaborative working style, with strong attention to animal welfare and experimental documentation.
- Good written and spoken English. What we offer
- Find out more: https://www.uzh.ch/de/explore/work.html. Work-Life Balance
- Flexible working models (such as part-time positions, mobile working, job-sharing)
- Childcare at the kihz foundation of UZH and ETH More Learning and Development
- Wide range of continuing education courses of UZH and the Canton of Zurich
Cosa offre l’azienda
- Our employees benefit from a wide range of attractive offers.
Processo di candidatura
- The Schwank Lab at the University of Zurich develops and translates next-generation genome-engineering technologies toward therapeutic applications.
- Our interdisciplinary research combines CRISPR-based genome editing, advanced delivery technologies, disease models, and preclinical studies, with major programmes in metabolic liver diseases, neurological disorders, and immune-cell engineering.
- A particular focus is the development of genome-editing therapies for urea cycle disorders, and we are currently advancing selected programmes toward clinical translation.
Dettagli ulteriori
- Good written and spoken English.
- Find out more: https://www.uzh.ch/de/explore/work.html.
- Childcare at the kihz foundation of UZH and ETH Learning and Development
- Language Center run jointly with ETH Zurich
- Food and drinks at reduced prices in the UZH cafeterias Lunch-Check-card with UZH contribution
- Special conditions on the Academic Sports Association ASVZ Free seasonal flu vaccinations
- Rest and relaxation at the quiet room in the university tower
- Digitalization: Hardware, software, mobile phone subscriptions Conditions of Employment Policies of the UZH
- Most UZH staff are employed according to public law International Services
- Support for people from outside Switzerland
Note e contenuto originale
- Your profile
- What we offer
- Work-Life Balance
- Childcare at the kihz foundation of UZH and ETH
- Learning and Development
- Food and drinks at reduced prices in the UZH cafeterias
- Lunch-Check-card with UZH contribution
- Healthcare
- Special conditions on the Academic Sports Association ASVZ
- Free seasonal flu vaccinations
Domande frequenti su questo annuncio
Che stipendio offre Universität Zürich per questa posizione?
Universität Zürich indica CHF 91'500 - 128'000 lordi annui per questo ruolo a Zürich. Questo è lo stipendio pubblicato nell'annuncio originale (o, quando il datore non specifica una cifra, una stima realistica per ruolo e settore) — il calcolatore di questo sito lo converte nel netto reale una volta applicate imposta da frontaliere e contributi sociali.
È un ruolo a tempo pieno, e che tipo di contratto offre Universität Zürich?
Questo annuncio è una posizione a tempo pieno. Il tipo di contratto mostrato qui arriva direttamente dall'annuncio originale del datore di lavoro; conferma sempre orario esatto, preavviso e durata del periodo di prova con Universität Zürich durante il colloquio, perché questi dettagli possono variare anche all'interno della stessa categoria contrattuale.
Serve un permesso da frontaliere per un ruolo nel canton Zurigo?
I residenti UE/AELS nella zona di frontiera del paese confinante con il canton Zurigo possono richiedere il Permesso G; il datore di lavoro svizzero lo presenta all'ufficio della migrazione di quel canton dopo la firma del contratto. Regole sulla zona di frontiera e tempi di lavorazione variano per paese confinante e canton — verifica i dettagli con l'ufficio della migrazione del canton Zurigo o con HR durante il colloquio.
Come mi candido a questa posizione presso Universität Zürich?
Usa il pulsante "Candidati ora" in questa pagina — rimanda direttamente all'annuncio originale di Universität Zürich su jobs.uzh.ch, quindi la tua candidatura arriva direttamente nel sistema di gestione candidature del datore di lavoro. Frontaliere Ticino non raccoglie né inoltra candidature in proprio.
